Which of the following is NOT a reason that scientists classify organisms? A to organize organisms B to easily identify organisms C to determine the age of organisms D to ensure the use of a common language

Answers

Answer 1
D. To ensure the use of a common language. The others are legit reasons to classify organisms
Answer 2

The statement that is not a reason that scientists classify organisms is to determine the age of organisms. Details about classification of organisms can be found below.

What is classification?

Classification in biology refers to the system of arrangement of organisms into different groups and sub-groups on the basis of their similarities and differences.

Taxonomic classification involves the following aspects:

Identification of organismsNomenclature of organisms

Therefore, this means that the statement that is not a reason that scientists classify organisms is to determine the age of organisms.

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Related Questions

Of the over 11,600 applications to the USDA by seed producers for GE crops, how many were eventually deregulated and allowed to be sold?

Answers

Answer:

1,190 were eventually deregulated and allowed to be sold.

Explanation:

As you may already know, in order for a seed producer to sell transgenic seeds and plants, or any other genetically modified product, he will need to request an evaluation of his production. This is because it is necessary to guarantee that the transgenic seeds will not cause any harm to any living being, nor has the potential to become a pest.

However, the production of transgenic products has grown more and more each year, which means that the increase in requests for evaluation of production is increasing. As an example of this, we can mention the 11,600 requests to the USDA from seed producers for transgenics that have occurred since 1987, of which 1,190 were eventually deregulated and allowed to be sold.

Iridium is a substance found only in asteroids and other space objects. This graph shows the amount of Iridium found in different sediment layers of Earth. They are marked off into 17 sections representing time.

Iridium Levels graph shows Iridium levels in sediment layers. Beginning at sediment layer 1, iridium levels remain between 0 and 5, jumping to a level of 23 between layers 5 and 6, and decreasing to near starting levels at layers 14 through 17.

What most likely happened in sediment layer 5?

A massive volcano erupted, causing global warming and lava flow, which in turn caused mass extinction.
More iridium was produced by space objects and dumped by local factories.
A massive dust cloud formed, causing global cooling and a lack of sunshine. This in turn caused a lack of plants and a mass extinction.
Fewer impacts lead to a drop in iridium levels and a mass extinction caused by a lack of sunshine.

Answers

In sediment layer 5, more iridium was produced by space objects and dumped by local factories is likely to happened.

Sediment rocks are formed from pre-existing rocks or pieces of once-living organisms. They form from deposits that accumulate on the Earth's surface. Sedimentary rocks often have distinctive layering or bedding.

Sediment rocks are formed on or near the Earth's surface, in contrast to metamorphic and igneous rocks, which are formed deep within the Earth. The most important geological processes that lead to the creation of sedimentary rocks are erosion, weathering.

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Final answer:

The increase in Iridium levels in sediment layer 5 is likely due to an asteroid impact because iridium is primarily found in asteroids.

Explanation:

Based on the provided information, it is likely that the higher levels of iridium found between layers 5 and 6 are due to an asteroid impact. Iridium is a substance primarily found in asteroids and other space objects. An increase in iridium levels in a specific sediment layer would suggest an influx of material from space, such as an asteroid strike. Therefore, the spike in iridium does not align with the scenarios of a volcanic eruption, more iridium being produced locally or the formation of a dust cloud.

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How does the presence of water on Earth support life?

Answers

Answer:

Easy

Explanation:

In this regard, water is essential simply because it's a liquid at Earth-like temperatures. Because it flows, water provides an efficient way to transfer substances from a cell to the cell's environment.

How do you think organ systems respond when an organ is unable to function properly?

Answers

They send chemical signals

Types of genotypes of the gametes in an individual heterozygous for the FXN gene

Answers

Answer:

The types of gamete in a heterozygous individual for the FXN gene will be two. A dominant gamete, which contains the "A" allele and a recessive gamete, which contains the "a" allele.

Explanation:

When an individual is heterozygous for a given gene, it means that that individual has different gametes (related to that gene), with that, that individual will generate two types of gamete; a dominant gamete with the "A" allele and a recessive gamete with the "a" allele.

If the individual is homozygous dominant, he will only generate one type of gamete, which is the gamete with the "A" allele. however, if the individual is homozygous recessive, he will only generate one type of gamete, which is the gamete with the "a" allele.

Final answer:

In individuals heterozygous for a specific gene, such as the FXN gene, two types of gametes would be produced with different genotypes, carrying either the dominant or recessive allele of the gene. This principle is similar for both sex-linked and autosomal genes, crucial for understanding inheritance patterns.

Explanation:

The question involves understanding the types of genotypes produced by gametes in an individual heterozygous for a specific gene, taking the FXN gene as an example. The FXN gene is not explicitly dealt with in provided materials, but by analogy to information about X-linked genes and gamete formation, we can deduce necessary information. In the context of X-linked genetic crosses, such as those involving the Drosophila eye color, gametes from an individual heterozygous for a specific gene (like the FXN gene, if it were X-linked) would produce two types of gametes in terms of genotype.

In the case of a female heterozygous for an X-linked gene, the two types of gametes would contain either the dominant or recessive allele of the gene in question. If the gene were similar to the F8 or eye color genes in Drosophila (where 'X' represents the chromosome and the superscripts represent different alleles), the genotypes of the gametes would be XA and Xa where 'A' stands for the dominant allele and 'a' for the recessive allele, assuming full dominance in the heterozygous condition. For a male heterozygous for an X-linked gene, since males possess one X and one Y chromosome and no homologous pair for the X chromosome, they would be considered hemizygous, thus producing gametes either carrying the X chromosome with the gene or a Y chromosome without it, denoted as XAY and XY, respectively.

This concept can be extrapolated to any gene, including autosomal genes where individuals produce two types of gametes, carrying either allele of the heterozygous pair. Understanding this mechanism is crucial for comprehending how genetic variations are passed through generations, affecting phenotypic ratios in offspring.

A population of herbivores is at its carrying capacity for its habitat. Which factor is likely to result in a sudden rise in population that far exceeds the carrying capacity?
A.
birth of young
B.
emigration
C.
immigration
D.
introduction of a new limiting factor

Answers

Answer:

-immigration is likely to result in a sudden rise in population that far exceeds the carrying capacity.

Answer:

C. immigration

Explanation:

two ways in which carbon dioxide enters the atmosphere?

Answers

Atmospheric carbon dioxide comes from two primary sources—natural and human activities. Natural sources of carbon dioxide include most animals, which exhale carbon dioxide as a waste product. Human activities that lead to carbon dioxide emissions come primarily from energy production, including burning coal, oil, or natural gas.

Why is it commonly believed that carbon dioxide is responsible for global warming? Give at least 2 reasons.

Answers

Answer:

Scientists attribute the global warming trend observed since the mid-20th century to the human expansion of the "greenhouse effect"1 — warming that results when the atmosphere traps heat radiating from Earth toward space.

Certain gases in the atmosphere block heat from escaping. Long-lived gases that remain semi-permanently in the atmosphere and do not respond physically or chemically to changes in temperature are described as "forcing" climate change. Gases, such as water vapor, which respond physically or chemically to changes in temperature are seen

Explanation:

Why are station models important?

Answers

Answer:

Meteorologists created the station model to fit a number of weather elements into a small space on weather maps. This allows map users to analyze patterns in atmospheric pressure, temperature, wind speed & direction, cloud cover, precipitation, and other parameters.

compare and contrast microevolution and macroevolution

Answers

Answer: Microevolution happens on a small scale, while macroevolution happens on a scale that transcends the boundaries of a single species. Despite their differences, evolution at both of these levels relies on the same, established mechanisms of evolutionary change: mutation.

Explanation: brainliest please

Final answer:

Microevolution refers to small-scale changes within a species over a few generations, usually driven by processes like mutation, migration, genetic drift, and natural selection. Macroevolution refers to large-scale changes over geologic time that often result in new species or extinction.

Explanation:

The concepts of microevolution and macroevolution both refer to changes occurring in species over time, but they occur at different scales. Microevolution refers to the changes in allele frequencies in a population over time. These changes usually happen over a few generations and are often driven by processes like mutation, migration, genetic drift, and natural selection. For example, a bacteria population might evolve resistance to a particular antibiotic due to favoring the survival of individuals with resistant mutations.

Macroevolution, on the other hand, refers to larger-scale changes that occur over geologic time, often resulting in the emergence of new species (speciation), or extinction of existing ones. For instance, the evolution of mammals from a common mammalian ancestor is an example of macroevolution.

So, summarily, microevolution focuses on changes within species, while macroevolution studies the patterns and processes of species themselves over time.

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Which of the following is example of a scientific model?

Answers

Answer

solar system, a globe of earth

Answer:

A model of the motions of the sun, moon and earth (which you participated in last year) A model of predicting eclipses. Models that explain weather phenomena can be used to predict weather.

Explanation:

These are examples of a scientific model.

Give one example of two other body systems that work together and explain how they support eachother

Answers

Answer:

The Muscular and Skeletal systems work together to help the body move and keep a shape.

Answer:

The Circulatory System and the Nervous system

Explanation:

I realize this question has already been answered, but if anyone wants more than one, I'm here to help!

The nervous system keeps the heart beating, as well as regulating other things, like letting the body know when the circulatory system is damaged. In return, the brain is kept alive with a lot of blood being pumped up there by the heart, despite gravity pushing it down.

Hope this helps!

what are the best baits for catfish

Answers

Answer:

Expmple

Nightcrawlers. Nightcrawlers remain a great bait for all cats, sometimes unequaled for channel cats. ...

PLEASE HELP


Growth hormone and insulin are protein hormones that regulate carbohydrate metabolism by hepatocytes (liver cells) through the activation of intracellular signaling pathways. Researchers investigated whether the two hormones trigger the same or different intracellular signaling pathways in hepatocytes. The researchers added either growth hormone or insulin to parallel cultures of hepatocytes. At several time points after the hormone addition, they purified total intracellular protein from the cells and quantified the level of the phosphorylated forms of two proteins involved in two different signaling pathways (Figure 1, A and B).


(a) Describe the first interaction that triggers signaling to begin in a target cell.

(b) Identify a dependent variable in the experimental design. Identify a negative control for the effects of hormone addition. Identify a likely reason why the researchers continued their experiment for 240 minutes.


(c) Describe the hormone and signaling protein combination that produced the greatest and most prolonged response. For the phosphorylated STAT5 response that reached 100 percent at 10 minutes in Figure 1A , calculate the rate of decrease (percent decrease per minute) in the detected level of phosphorylated STAT5 from 10 to 30 minutes.


(d) The researchers claim that the similar regulation of carbohydrate metabolism by hepatocytes when the cells are treated with growth hormone or insulin results from the activation of different signaling pathways. Use the data from the researchers’ experiment to support their claim.

Answers

Answer a:

In the case of growth hormone, it activates the STAT5 signaling pathway. Therefore, initially, as the hepatocytes sense growth hormone, they imitate the STAT 5 pathway, which after some time maintains a steady rate.

In the addition of insulin, it activates Protein kinase B pathway initially.

Answer b:

The dependent variable in the experiment is the level of STAT 5 and protein kinase B proteins. Those proteins are depending upon the independent variables growth hormone and insulin. A negative control should be the addition of the same amount of water into hepatocytes, which will give no effect to the protein levels.

The researcher wants to identify short and long term effects of both hormones in terms of whether the signaling pathway interacts with each other or not and to identify the steady-state of the signaling pathway. That is why the researcher run the experiment for 240 minutes.

Answer c:

Insulin and protein kinase B interaction is the greatest and most prolonged response as is seen in the graph. Protein kinase B level reached to 100 after 30 minutes as insulin added while the level remained to near 80 even after 240 minutes.

The level of STAT 5 at the 10th minute = 100

The level of STAT 5 at 30th minute = 35

From 10 to 30 minutes, the level of STAT 5 = 100 – 35

From 10 to 30 minutes, the level of STAT 5 = 65

Duration = 30 – 10 minutes

Duration = 20 minutes

Rate of decrease = 65/20

Rate of decrease = 3.25 levels/min

Answer d:

The claim by the researcher is supported because of the known functions of insulin and growth factors. Both hormones have a tendency to respond to the presence of glucose. The growth hormone initiates STAT5 signaling for producing the Igf-1 factor that is important for utilizing glucose. The insulin hormone is well known for utilizing glucose.

Which describes the mating of organisms that have different homozygous alleles for a single trait?

Answers

Explanation:

monohybrid crossdihybrid crosshomozygous crossheterozygous cross The term which describes the mating of organisms that have different homozogous alleles for a single trait is monohybrid cross . The 'mono' refers to the singular trait while 'hybrid' refers to the crossing of two different parents.

Two fruit flies that are heterozygous for body color and eye color are crossed. Brown body color is dominant to black body color. Red eye color is dominant to brown eye color.

Answers

Answer:

For body color 75% of the fruit flies are dominant for the trait

For Eye color 75% of the flies are dominant for this trait

Answer:

9:16, 3:16, 3.16, 1:16

Explanation: on edge

write out the chemical formula for a compound that has 18 carbon atoms, 26 hydrogen atoms, 1 chlorine atom, 3 nitrogen atoms, and 1 oxygen atom?

Answers

Final answer:

The chemical formula for a compound with 18 carbon atoms, 26 hydrogen atoms, 1 chlorine atom, 3 nitrogen atoms, and 1 oxygen atom is C₁₈H₂₆ClN₃O.

Explanation:

To write out the chemical formula for the compound with the specific number of atoms, we list each element symbol followed by its corresponding subscript number that represents the quantity of each element present in the molecule. In this case, the compound you've described contains 18 carbon (C) atoms, 26 hydrogen (H) atoms, 1 chlorine (Cl) atom, 3 nitrogen (N) atoms, and 1 oxygen (O) atom. Therefore, the chemical formula for this compound would be C₁₈H₂₆ClN₃O.

is the biosphere thicker above or below sea level

Answers

Answer:

Traditionally, the biosphere is considered to extend from the bottom of the oceans to the highest mountaintops, a layer with an average thickness of about 20 kilometers. Scientists now know that some forms of microbes live at great depths, sometimes several thousand meters into the earth's crust.

Explanation:

The biosphere is not thicker in any specific location, including above or below the sea level.

What is a biosphere?

The biosphere refers to the portion of the earths surface where life exists, and it  encompasses all the living organisms and the environment they occupy, including both terrestrial and aquatic ecosystem.

The biosphere is a complex and dynamic system that encompasses a wide range of ecosystems, from the deepest parts of the ocean to the highest points of the mountains.

So, whether the biosphere is thicker above or below sea level depends upon the specific location and the types of ecosystems present. In some areas the biosphere ca n be dominated by terrestrial such as forests or grasslands ecosystem, while in other areas it is dominated by aquatic ecosystems such as coral reefs or mangrove forests.

Therefore, there is not any specific location where the biosphere is thicker above or below the sea level, as it depends upon the specific location.

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How can you tell if your heart is breaking?

Answers

Answer:

When you feel your heart cave in and it sorta physically hurts...

the life cycle of a white wagtail

Answers

The eggs begin to hatch after 12 days (sometimes as late as 16 days). Both parents feed the chicks until they fledge after between 12 and 15 days, and the chicks are fed for another week after fledging. They will then repeat what the would do having eggs with a mate and then eventually die.
Final answer:

The life cycle of a white wagtail starts from mating, laying of eggs, hatching, fledgling stage, and finally adulthood. As they mature, they develop distinctive markings and undergo annual migrations. The change of climate is vital for maintaining a constant body temperature and survival.

Explanation:

The life cycle of a white wagtail, like other birds, begins with mating and the laying of eggs. The parents take care of the eggs, which will then hatch into hatchlings. The hatchlings, still dependent on their parents, continue to grow until they become fledglings, where they can nearly take care of themselves. Eventually, they will mature into adult wagtails capable of starting their own families.

During each stage of the life cycle, the white wagtails go through changes specific to their species. For instance, they develop distinctive feather colors as they mature and undergo annual migrations for suitable mates and habitats, similar to the American white pelican.

Migration is an important aspect of the life cycle of many bird species, including the white wagtail. During migration, they also adjust to warmer climates to maintain a constant body temperature which is crucial for their survival and ability to reproduce.

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PLEASEEE ANSWER IN NEXT 5 MIN Why do the cells need time to recover after the heat shock?

Answers

Answer:

Following heat shock or electroporation, transformed cells are cultured in antibiotic-free liquid medium for a short period to allow expression of antibiotic resistance gene(s) from the acquired plasmid to begin (Figure 5). This step improves cell viability and cloning efficiency.

Final answer:

Cells need time to recover after a heat shock to refold misfolded proteins with the help of heat shock proteins (HSP), ensuring proper cell function and survival.

Explanation:

Cells need time to recover after a heat shock because the increase in temperature can damage proteins, causing them to misfold. Heat shock proteins (HSP) are a class of chaperones that aid in refolding these damaged proteins. When cells are exposed to high temperatures, they activate these heat shock proteins by releasing them from the NR/HSP complex and increasing the transcription of HSP genes. The recovery period allows these proteins to repair and refold misfolded proteins, ensuring that the cell maintains proper function and avoids the accumulation of damaged proteins which could lead to cell death.

In the wake of a heat shock, cells enter a lag period where they may need to synthesize RNA, enzymes, and other essential metabolites to adapt to environmental changes and repair any damage incurred. This is crucial for cell survival as continued stress without the chance to recover can result in cell death.


What is the flexible connective tissue shown in blue?

tendon
bone
cartilage
muscle
right answer gets brainliest!

Answers

Answer:

Cartilage

Explanation:

Final answer:

The flexible connective tissue shown in blue is cartilage.

Explanation:

The flexible connective tissue in the shoulder joint is primarily cartilage. Cartilage is a tough and resilient tissue that covers the ends of bones where they meet in a joint, providing a smooth surface for low-friction movement. In the shoulder, it is found in the glenoid cavity of the scapula (shoulder blade) and the head of the humerus (upper arm bone).

This articular cartilage reduces friction and cushions the joint during various movements like arm rotation and lifting. While cartilage plays a crucial role in the shoulder joint's flexibility and function, it can be susceptible to wear and tear, leading to conditions like osteoarthritis.

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A diverse pool of _____________ helps ensure that individuals in a species will pass a variety of traits to their offspring.
A. Genes
B. Populations
C. Fish

Answers

Answer:

A. genes

Explanation:

Answer:

a

Explanation:

5. Fruits, nuts and vegetable production are classified as which ore
benefits of the horticulture industry?
A. Aesthetic value
B Recreational value
C. Therapeutic value
D. Food production

Answers

Answer
Food production

Insulin helps maintain glucose levels in the blood. If blood glucose levels got very high, what would you expect to see happen to insulin levels?

Answers

Insulin and glucagon are hormones that help regulate the levels of blood glucose, or sugar, in your body. Glucose, which comes from the food you eat, moves through your bloodstream to help fuel your body.

Insulin and glucagon work together to balance your blood sugar levels, keeping them in the narrow range that your body requires. These hormones are like the yin and yang of blood glucose maintenance. Read on to learn more about how they function and what can happen when they don’t work well.

A wave is traveling through X. What can be known about X?
It is empty space.
It is any medium
It is a solid.
It is a liquid.

Answers

Answer:

B. it is any medium

Explanation:

A wave is traveling through X. Here, X can be any medium. Therefore, option B is correct.

What are waves and their types?

A wave is an energetic disturbance in a medium that doesn't include any net particle motion. Elastic deformation, a change in pressure, an electric or magnetic intensity, an electric potential, or a change in temperature are a few examples.

In most cases, the impact of winds on the ocean's surface is what generates waves. The ocean's surface water particles are driven downward by winds. Once more, water vapor rises above the surface.

There are mainly two types of waves and that are longitudinal and transverse waves. They travel through a medium. Thus, a wave is traveling through X. Here, X can be any medium. Therefore, option B is correct.

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What role does blood play before cellular respiration can occur

Answers

Answer: Blood carries the oxygen through out the body and gets re-oxygenated to keep the body going.

Answer: C Blood delivers oxygen and glucose to cells.

Explanation: Blood plays a very important role before cellular respiration. The blood provides oxygenated blood for the aerobic processes that takes place during cellular respiration. Glycolysis, link reaction, Kreb's Cycle and Electron Transport Chain are all the aerobic process of Cellular respiration that requires oxygen.

PLEASE FAST 15 points!!!
29. Which of the following is true about a larger cell?
A. More wastes must leave the cell.
B. More molecules must move through the membrane.
C. Distances from the cell membrane to various organelles are greater.
D. all of the above

30. To reduce the dependence on diffusion, multicellular organisms have
A. reduced cell size and the number of cells
B. developed thinner cell membranes
C. developed other internal transport systems
D. all of the above

Answers

Answer:

Explanation:

29. d all of the above

30.  c

Answer: 29. D. all of the above

30. C. developed other internal transport systems

Explanation:

describe the process of water changing state

Answers

Answer:

Explanation:

Water freezes into ice heats up and boils to steam

Answer:

Substances can change state, usually when they are heated or cooled.

The closeness, arrangement and motion of the particles in a substance change when it changes state.

If water turns to gas, (for example steam) the particles move more freely with each other and if it turns to solid (ice) the particles are packed more closely together.

To change into gas, water needs to be heated and to change into a solod water needs to be freezed

Explanation:.


PLZ HELP 13+points
A population of lizards lived in an ecosystem that was prone to flooding. After many generations, most of the lizards in the population had longer legs than their ancestors, which helped them flee from floods. Which statement best explains this change? *

A)The lizard genes spontaneously mutated to address the flooding threat.
B)Genetic variation among lizard limbs allowed for natural selection to occur.
C)The limbs were artificially selected because humans probably caused the flooding.

Answers

Answer:

B)Genetic variation among lizard limbs allowed for natural selection to occur.

Explanation:

Natural selection is the phenomenon in which creatures evolve as time goes on. This evolution occurs when the species experiences a certain natural challenge that it can adapt to. Lizards that had short legs died in the floods while the lucky longer legged lizards were able to pass on their genes to the next generation. This is Natural Selection in action.

Answer:

B

Explanation:

When the lizard go through natural selection, they evolve to the threat of flooding. Henceforth, they grow longer legs. The genes for longer legs will continuously be passed down to more and more generations.

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Which set of drivers are progressing at the same pace Which of these activities is most likely to cause the spread of disease?sneezing into the sleeve of a shirteating contaminated foodwashing hands before eatingstaying at home when sick If no safe shelter is available during an electrical storm,___on the ground away from water. Based on this behavior, do you think that the people of the Capital actually care about the tributes and think of them the same way theyd think about their own children? Click the prime number cards to build composite numbers to 50. Which of the following best defines instantaneous speed? (3 points)It is a measure of how far an object moves in a certain time.It is the total distance traveled over the total time.It is the speed of an object in a specific direction. Dialogue requires special rules of punctuation true or false factorise 4p + 6pq step by stepanswer fully please, thank you. Study carefully the meeting between Stephen and Jarvis in Chapter 36. What do we learn about the two men, and about the nature of their relationship? Which statement BEST describes the type ofevidence Washington provides for his claim onpage 2 that Harvard University is helping to solvethe problem of racial inequality?He uses specific examples of how lowly cabins havebeen transformed into mansions.He provides specific examples of how cotton fieldsand sugar bottoms have been changed.He makes general statements about the importanceof competition and success.He uses general statements about creatingrelationships between the wealthy and the poor. Read the sonnet. Then, identify the rhyme scheme and the type of sonnet. Your hands lie open in the long fresh grass, - The finger-points look through like rosy blooms: Your eyes smile peace. The pasture gleams and glooms 'Neath billowing skies that scatter and amass. All round our nest, far as the eye can pass, Are golden kingcup-fields with silver edge Where the cow-parsley skirts the hawthorn-hedge. 'Tis visible silence, still as the hour-glass. Deep in the sun-searched growths the dragon-fly Hangs like a blue thread loosened from the sky: - So this wing'd hour is dropt to us from above. Oh! clasp we to our hearts, for deathless dower, This close-companioned inarticulate hour When twofold silence was the song of love. What type of sonnet is this A_____is a solid consisting of a square,a point not in the same plane as the square and all the points between them I NEED HELP PLZ!!!! Its important! Picture #1using the facts : write a caption ( journalism ) Which volcanoes are located at hot spots? what does it mean that there is an equal theoretical probability of each outcome ? aWhat is the vanishing point?the point where you can no longer see the imagethe point where all imaginary lines convergethe point where the image fadesd all of the above Read this excerpt from A Black Hole Is NOT a Hole.Friction is what makes your hands warm up when you rub them together really fast, or what makes rubber burn when a car screeches to a halt, tires skidding on the road.Which statement best identifies the description in this sentence?A.Examples are used to describe friction.B.A characteristic of warmth is described.C.Examples are used to describe car tires.D.A feature of burned rubber is described. WILL MARK BRAINLIEST What is the value of P(X=2 or X=0)=? Graph the circle which is centered at (-5,1) and has a radius of 4 units Steam Workshop Downloader