In numerous studies, treatment of prion preparations with ionizing and uv-radiation does not reduce transmission of disease, however, treatment with denaturants reduces disease transmission. what can be inferred from these observations? choose all the true statements.

Answers

Answer 1

The treatment of prions with denaturants reduces disease transmission because prions do not contain genetic information, which is affected by ionizing radiation.

Further Explanation:

Disease transmission can be defined as a process which involves the transfer of infectious agent from one individual to another. This transmission can be direct or indirect depending upon the mode of the transfer of the agent to an individual.

The term prion refers to protein infection particle. Normal prion protein is a protein on the surface of the cells which is encoded by a PRNP gene. Mutation in the PRNP gene results in abnormal or misfolded prion protein. Altered prions contains proteinaceous infectious particle which can transmit disease by inducing normal proteins to become misfolded ones.

Treatment of prion preparations with ionizing and UV-radiation does not reduce transmission of disease as it is not a genetic material or DNA. Denaturants can reduce disease transmission by denaturing the structure of misfolded protein which cannot reform again to become infectious.

Learn more:

1. Learn more about plants: https://brainly.com/question/862697

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3. Learn more about viruses: https://brainly.com/question/3889603

Answer Details:

Grade: College Biology

Subject: Biology

Chapter: Life processes-Virus

Keywords:

Prion, protein infection particle, proteinaceous infectious particle, denaturants, misfolded protein, PRNP gene.

Answer 2

Prions' resistance to ionizing and UV radiation suggests that they do not contain nucleic acid genomes, and their infectivity being reduced by denaturants confirms the role of protein structure in disease transmission. Their robustness necessitates special handling guidelines in medicine and related fields to prevent transmission of transmissible spongiform encephalopathies.

From the observations that ionizing radiation and UV radiation do not reduce the transmission of disease caused by prions, but treatment with denaturants does, it can be inferred that prions are not inactivated by methods that damage nucleic acids, such as ionizing and UV radiation. This suggests that prions do not rely on nucleic acid components like DNA or RNA for their infectious properties, which is consistent with the fact that prions do not contain their own genome. Since denaturants, which disrupt protein structures, do reduce transmission risk, it underscores the role of the abnormal protein conformation in prion infectivity. This aligns with the unique nature of prions as infectious agents that are composed solely of misfolded protein.

Prions are particularly resistant to methods that typically destroy other infectious agents. This information is critical in fields that deal with transmissible spongiform encephalopathies (TSEs), and it guides the development of safety practices for handling prions. The guidelines must address the robustness of prions and the specific ways to reduce their infectivity, emphasizing the importance of using denaturants over other, less effective methods.


Related Questions

Think about what you know about science today. How do you think scientific knowledge will be different in 100 years? Explain your answer.

Answers

Answer:

We will know more about the world around us as we continue to collect data.

Much of the basic knowledge we have now will still be important.

There will be new technologies that allow scientists to explore the world in different ways.

Explanation: edge 2022

The word science surrounds the whole universe. This word may be defined as the complete source of knowledge that is concerned with the external world. It also has implications for the inside of an organism.

What is Scientific knowledge?

Scientific knowledge may be defined as information or source of implications that are estimated through the utilization of scientific methods. They include observations, hypothesis, methodology, conclusion, evidence, etc.

The scientific knowledge will be different in 100 years because there must be the development of technologies that assist scientists to explore more in a much broader sense.

Therefore, it is well described above.

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Seasonal variations in the color of the snowshoe hare's fur is an example of ________

Answers

A seasonal variation in the color of the snowshoe hare’s fur is an example of environmental cues fluctuating gene expression. Gene expression is a progression by which the proprietorship of a gene leads to the presence of the phenotype of the equivalent character.


What type of cellular transport do they use for large molecules? what features of the cell membrane permit it?

Answers

this is called active transport or fully permeable

Answer: The type of transport that amoebas use for large molecules is endocytosis and exocytosis.

Explanation: Endo- and exocytosis are two types of active transport. In both of these forms of transport, small spheres of membrane called vesicles are used to move molecules.

Identify what structures in a skeletal muscle will shorten in length during contraction of the muscle. choose all that apply. (0.5 pts)
a. the skeletal muscle itself (the whole muscle organ)
b. muscle fascicle
c. muscle fiber
d. myofibril and. sarcomere f. thin filament g. thick filament

Answers

Final answer:

Muscle fibers, myofibrils, and sarcomeres shorten in length during muscle contraction.

Explanation:

During muscle contraction, the structures that shorten in length include:

Muscle fibers: Muscle fibers are the individual muscle cells that make up a skeletal muscle. They contain myofibrils that shorten during contraction.Myofibrils: Myofibrils are tiny structures within muscle fibers that consist of protein filaments called actin and myosin. These filaments slide past each other, causing the myofibrils to shorten.Sarcomeres: Sarcomeres are the functional units of a muscle fiber. They are composed of overlapping actin and myosin filaments. During muscle contraction, sarcomeres shorten as the actin and myosin filaments slide past each other.

Which immune cells are disrupted when a child is infected with human immunodeficiency virus (hiv)?

Answers

The cells that are disrupted are the CD4+ cells

What are the psychosocial effects of BDD?

Answers

Body dysmorphic disorder, also known as BDD, is defined in the Merriam-Webster dictionary as a pathological preoccupation with an imagined or slight physical defect of one’s body to the point of causing significant stress or behavioral impairment in several areas (as work and personal relationships)












Final answer:

Body Dysmorphic Disorder (BDD) leads to severe psychosocial effects such as depression and anxiety, heightened self-consciousness, unhealthy coping mechanisms like substance abuse, and stress particularly related to puberty.

Explanation:

Body Dysmorphic Disorder (BDD) has profound psycho-social effects on individuals suffering from it. These include negative impacts on interpersonal relationships, mental health, and typical social functioning. Here are some key psychosocial effects of BDD:

Depression and Anxiety: People with BDD often experience co-morbid disorders, including depression and anxiety (Al-Asadi, Klein, & Meyer, 2015). This can result in feelings of sadness, hopelessness, and a constant state of worry and fear. Self-consciousness: Individuals with BDD are overly concerned with their appearance, leading to severe self-consciousness and embarrassment. They often avoid social interactions and can become quite isolated (Falagas et al., 2007). Unhealthy Coping Mechanisms: Due to the mental distress caused by BDD, individuals may resort to unhealthy coping mechanisms, such as substance abuse or self-harm (Wisner et al., 2013). Stress related to puberty: Puberty can exacerbate feelings of self-consciousness, which can be particularly challenging for individuals with BDD (Ge, Conger, & Elder, 2001).

It's vital to provide support to individuals with BDD to mitigate these psychosocial effects and promote overall well-being.

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Which part of the brain regulates hunger and thirst

Answers

I think the answer is: Hypothalamus

Final answer:

The hypothalamus in the brain regulates hunger and thirst by receiving neural and hormonal signals, which indicate when to eat and when you are full.

Explanation:

The part of the brain that regulates hunger and thirst is the hypothalamus. It functions as the main control center, integrating various neural and hormonal responses from the digestive system. The hypothalamus contains neural circuits that respond to chemical signals indicating nutrient levels in the blood, as well as mechanical signals from the stomach regarding its fullness. These responses determine whether we feel the need to eat or the sensation of satiety. Additionally, fat tissue produces the hormone leptin, which communicates with the hypothalamus to help regulate food intake and energy balance.

During emerging adulthood, all body systems _____. function optimally age rapidly cease developing begin to develop

Answers

function optimally

Emerging adulthood covers the age between 18 to 25 years old. During this stage of development, 68.4% of young adults reported that their physical health was either very good or excellent, and oftentimes, childhood ailments, such as asthma, are outgrown. Because body systems function optimally at this stage, it is an ideal time for physical work and successful reproduction. 

Biological rhythms that occur on a daily basis are called _____ rhythms.

Answers

Answer:  "circadian" .
_____________________________________________

Approximately 80 percent of the illicit drugs smuggled into the united states are interdicted (stopped) at the border.
a. True
b. False

Answers

I would say false

Approximately 80 percent of drugs smuggled into the border are from mexico so that's probably where they get the '80%' from. 

What occurs when an earthquake causes a sudden vertical change in the sea floor? a. isostasy b. soil creep c. sheet erosion d. a tsunami


apex D. a tsunami

Answers

D. A Tsunami would occur

Answer: d. Tsunami

A tsunami is a natural disaster in which high speed waves generate in the ocean due to the gravitational force exerted by the moon on the water of the ocean resulting in flood. But these may also occur because of the underwater earthquakes, landslides and volcanic eruptions. All these events causes changes in the sea floor.

Therefore, tsunami will occur when an earthquake causes a sudden vertical change in the sea floor.  

Which body of water is home to the ENSO cycle?

Answers

equatorial Pacific Ocean


The correct answer is equatorial pacific ocean.

Equatorial pacific ocean is a body of water is home to the ENSO cycle.

ENSO cycle refers to southern Oscillation or El Nino. The interaction which occurs between ocean and atmosphere in tropical pacific results to periodic differences.

The three phases of ENSO include La nina, El Nino and neutral phase. ENSO lasts for nine to twelve months. They mostly develop on March to June and weaken on May to July.

ENSO is caused when atmospheric pressure across the pacific of equatorial.

An individual who cannot access memories created before brain damage or injury is suffering from _____ amnesia.

Answers

The inability to access memories formed, or difficulty in retrieving them, before brain damage or injury is called a Retrograde Amnesia
It is caused by impairment to the memory-storage areas of the brain. This type of damage can result from a distressing injury, a serious illness, a seizure or stroke, or a degenerative brain infection. It can be temporary, permanent, or get worse over time depending on the cause. With this type of amnesia, memory loss typically involves facts instead of skills. For instance, a person might forget if he owns a car, what make and model it is, or when he bought it, but he will still know how to drive.

The main hazard from a quiet volcanic eruption is a. volcanic gases. b. lava flows. c. geysers. d. pyroclastic flows.   Please select the best answer from the choices provided

Answers

The answer is B) lava flows 
Final answer:

The main hazards from a quiet volcanic eruption are volcanic gases and lava flows. These can have substantial long-term effects on the atmosphere, climate, and terrestrial landscapes. Explosive phenomena like geysers and pyroclastic flows are more characteristic of violent eruptions.

Explanation:

The main hazard from a quiet volcanic eruption is not geysers or pyroclastic flows, as these usually occur in explosive eruptions. Instead, the primary dangers are a. volcanic gases and b. lava flows. Volcanic gases, such as water vapor, carbon dioxide, and sulfur dioxide, are released massive quantities during eruptions. These gases can have long-term effects on the atmosphere and climate. Furthermore, even quiet eruptions can produce enormous amounts of lava. Lava flows can spread rapidly from long cracks during an eruption, forming vast lava plains, like those that exist on the Moon and some of the other terrestrial planets. These flows can cover large areas, causing significant harm to human settlements and ecosystems.

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Why would removing eosin y and/or methylene blue from emb agar alter the medium's sensitivity or specificity/?

Answers

EMB agar is a selective medium for gram negative bacteria. It is a selective and differential medium for coliform. EMB agar contain eosin which is toxic to gram positive bacteria; the function of eosin is to inhibit the growth of gram positive bacteria and to react with lactose fermenter.
Eosin thus customize EMB agar for gram negative bacteria and removing it from the agar will alter the medium sensitivity.

Ou have screened for several new recessive mutations in a species of wasp. wasps homozygous for apricot (aa) have pale orange eyes. (wild-type eyes are brown.) wasps homozygous for blunt (bb) have short wings. (wild-type wings are long.)

Answers

Mutation in the gene encoding the recently isolated WASP protein has now been identified as the genetic defect responsible for the X-linked Wiskott-Aldrich syndrome (WAS), a primary immunodeficiency disease associated with extensive phenotypic variability.

The non-recombinant gametes are AB and ab which are found in the parents whereas aB and Ab are recombinant in nature as they are absent in parent genotype.

Further explanation:

The true-breeding or pure-breeding represents the parents that are homozygous in nature and will pass on the specific trait to the progeny as they contain either recessive or dominant alleles but not both. The parents heterozygous for a trait will not be able to produce exactly the same phenotype in the offspring due to the presence of both types of alleles.  

The genotype of pure-breeding double-mutant can be depicted as ‘aabb’ for apricot and blunt while the wild-type genotypes can be considered ‘AABB’. The cross between the mutant and wild type genotypes would result in the progeny with only ‘AaBb’ genotype.

Parent:   aabb × AABB

Filial 1 (F1) generation: AaBb

The F1 hybrids are then test crossed with double-mutant line and result as follows:

AaBb × aabb

 F2 generation:

The genotypes obtained in the F2 generation are AaBb, Aabb, aaBb, and aabb which have the phenotypes wild-type, wild-type apricot, pale orange-wildtype, and double-mutant, respectively.  

AB, Ab, aB, and ab are the haploid genotypes that were received as gametes from the F1 generation. The gametes Ab and aB are considered recombinant while gametes ab and Ab are said to be non-recombinant because the recombinant gametes are not found in the parents while the non-recombinant ones have been transferred from the parents.

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Answer details:

Grade: College Biology

Subject: Genetics

Chapter: Gene Interactions

Keywords:

Gametes, recombinant gametes, non-recombinant gametes, pure-breeding, true-breeding, F1 generation, F2 generation, genotypes, phenotypes, recessive allele, dominant allele, wild-type, mutant.

 

Cellular (aerobic) respiration takes place in the presence of and with the use of which o the following?

water

carbon dioxide

oxygen

sunlight

Answers

In the presence of oxygen

Cellular (aerobic) respiration takes place in the presence of and with the use of the following: oxygen.

Cellular respiration is the process that converts stored food or glucose into energy called ATP with carbon dioxide and H2O as byproducts. Cellular respiration is either aerobic or anaerobic respiration.

Aerobic respiration is divided into three main stages: Glycolysis, the Citric acid cycle, and electron transport chain.Oxygen is needed to help the process of turning glucose into ATP. The initial step releases just two molecules of ATP for each glucose.The later steps release much more ATP.Most of the reactions of cellular respiration are carried out in the mitochondria.

Thus, Cellular (aerobic) respiration takes place in the presence of and with the use of the following: oxygen.

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What enzyme came from the digestive tract of the mondoni

Answers

I found the full exercise on the internet and it describes that there are three enzymes and you want to know which are the two enzymes from the digestive tract of the mondoni and which one is the enzyme from a hot spring.
Attached are two graphs from the analysis of the activity of these enzymes regarding temperature and pH. I found these graphs with the full exercise.
The enzymes that probably came from the digestive tract of the mondoni were enzymes A and B. These enzymes were resistant two lower levels of pH which indicates that they could be present in a digestive tract, which tends to be acidic, while the enzyme C does not tolerate lower pH levels. Enzymes A and B were also more active when in lower temperatures that match temperatures of a normal living organism, whereas enzyme C was more active in higher temperatures matching its probable provenience - a hot spring.
Final answer:

The question refers to an enzyme from the digestive tract of a 'mondoni', which could be a mistake or misinterpretation. In general, organisms like 'mondoni', if they exist, would have enzymes like amylase, lipase, and protease in their digestive tract to break down food for absorption.

Explanation:

The question doesn't specify a particular enzyme related to the digestive tract of the 'mondoni,' which appears to be a misspelling or misunderstanding. However, generally speaking, organisms have multiple enzymes that function in the digestive process. Enzymes like amylase, lipase, and protease work to break down carbohydrates, fats, and proteins respectively into their smaller constituent parts for absorption and utilization in the body. Amylase breaks starches into simple sugars, lipase splits fats into glycerol and fatty acids, while proteases break proteins into amino acids. If the 'mondoni' refers to a specific organism, a further and more accurate answer may require additional information about the organism.

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one of the effects of hurricane Katrina, which devastated new orleans in 2005 was the death of almost all of the plants in flooded areas. initially, toxic chemicals and bacteria were suspected as a possible cause. Scientist later determined that the salt concentration in the floodwater caused the plants to die. The death of the plants was most likely due to? A. water moving into plant cells from the surrounding environment. B. Water moving out of plant cells into the surrounding environment.
C. both water and salt moving from plant cells into the surrounding environment.
D. both water and salt moving into plant cells from the surrounding environment.

Answers

 B. Water moving out of plant cells into the surrounding environment is the cause of the plants death in flooded areas in New Orleans in 2005 because of the hurricane Katrina. Since the floodwater has a salt concentration that penetrates into the plant cells.




Final answer:

The plants in the flooded areas of New Orleans died after Hurricane Katrina in 2005 due to the high salt concentration in the floodwaters. This caused water to move out of the plant cells (plasmolysis) leading to dehydration and death.

Explanation:

The death of the plants in the flooded areas of New Orleans after Hurricane Katrina in 2005 was most likely due to B: Water moving out of plant cells into the surrounding environment. This effect is largely related to the concept of osmosis. Essentially, the high salt concentration in the floodwaters created a hypertonic environment, causing the water in the plant cells to move out towards the saltier environment in a bid to balance the concentration. This process, known as plasmolysis, results in dehydration and ultimately the death of the plant.

Furthermore, some plant species, known as halophytes, can tolerate such salty conditions due to special adaptations. However, the majority of the plants in the flood-hit areas of New Orleans were not halophytic, thus could not withstand the high salt concentrations. This demonstrates that while some organisms can well regulate the effects of osmosis, many cannot when faced with extreme conditions.

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How can scientific knowledge impact a decision about treating a disease outbreak?

Answers

Well scientific knowledge can help with diseases because say for ex: scientist 1 and scientist 2 are trying to treat breast cancer on a girl, they do the exams and tests on her and all, but when they receive some news about cures or risks and etc, they may improve their methods, be more cautious, or use more techniques, so its basically like a preparation tool for scientists so they know what's ahead.

Scientific knowledge may be able to tell us what the disease is immune to, and which kind of cure would actually work against the disease present, and which would be ineffective or may even help the disease spread and mutate.

hope this helps

Which organelles' function is primarily locomotion?

Answers

Flagellum is organelle primarily for locomotion.
Final answer:

The main organelles linked with cell locomotion are flagella and cilia. They are found in both eukaryotic and prokaryotic cells, with structural differences. Other contributing organelles include pseudopodia in amoeba and flagellum in Euglena.

Explanation:

The primary organelles associated with locomotion, or movement within cells, are flagella and cilia. These organelles are found in both prokaryotic and eukaryotic cells, though their structures are distinct. In eukaryotic cells, the flagellum resembles a flexible whip and is made up of nine parallel pairs of microtubules surrounding two central ones, which are arranged in a 9+2 array. The cilia are similar to flagella but shorter and can be used for locomotion, feeding, or the movement of extracellular particles.

Other organelles that contribute to locomotion include pseudopodia in amoeba, which are lobe-like extensions used to anchor the cell to a surface and pull it forward, and the whip-like flagellum in Euglena.

It's important to note that these organelles not only enable the cells to move independently, they also help maintain the cell's shape, secure other organelles in specific positions, and allow the cytoplasm and vesicles to move within the cell.

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The location (room) in which a surgery can be conducted is not dependent on which factor?

Answers

The location in which a surgery can be conducted that should no dependent on the species of the surgical patient. Because all human are equal in the body so in surgery time it does not consider the species of the patient. If we consider only Whether the surgery is survival or non-survival. Whether a surgery is major or minor. The source of funding.

The first step of the ted five-step protocol for effective presentations is to plan your delivery.
a. True
b. False

Answers

The answer is false because the second step of the TED 5 step protocol is the planning of your delivery. The first step of the TED 5 step protocol is the framing of your story, therefore, the answer is false. 

Which of these is an advantage of using wind as a source of energy? A. Wind energy doesn't pollute the air.
B. Wind turbines take up a lot of space.
C. Wind turbines can produce noise pollution.
D. Wind turbines can harm local wildlife, such as birds.

Answers

the answer to this question is A, as it states the positive effect of wind energy on the environment. 

Answer: A. Wind energy doesn't pollute the air.

Explanation:

Wind energy is a renewable source of energy due to abundance of wind in the atmosphere. The wind energy is harnessed by high speed wind currents used to run the wind turbine. The turbine convert the wind energy into electrical energy.

The wind energy does not generate pollutants like the energy generated by conventional fuels like fossil fuels.

A car has positive acceleration. what information can you infer from this? A. The car is changing direction B. The car is speeding up in the same direction as it traveling C. The car is slowing down is down and changing he direction it is traveling D. The car is slowing down

Answers

B
because velocity talks about the speed and direction of an object


Answer:

The correct answer is option B. "The car is speeding up in the same direction as it traveling".

Explanation:

A positive acceleration is defined as change of velocity upwards the direction that the object has taken. Therefore, a car having a positive acceleration means that the car is speeding up in the same direction as it traveling. Basically, after a positive acceleration, the car is traveling faster in the same direction that it was before.

when two plants, both tall, were crossed, they produce some offspring that were dwarves. Assuming that the height of the plant is controlled by a single gene and the allele for the tall plant is dominant, what is the genotype of the parents

Answers

The genotypes of the parents would have to be Tt and Tt. It could not be Tt and tt because both plants are tall. It could not be TT and Tt because then all offspring would be tall. The Tt cross would give offspring of TT, Tt, Tt, and tt, which fits all the requirements. 

The Answer is

D. Tt and Tt

What would happen to a neuron if it was exposed to tetrodotoxin?

Answers

If a neuron is exposed to tetrodotoxin ,sodium ions will be unable to cause the action potential,therefore being blocked from passing any impulses or receiving them...

How do biological organisms use energy worksheet answer key?

Answers

First, chemical energy from organic molecules is used to make ATP (Adenosine triphosphate) in cellular respiration, after which ATP provides energy for biological processes.

Answer:

Organisms use energy in two steps:

Conversion of food into adenosine triphosphate (ATP):

Organisms harness the chemical energy of the food and convert it into more usable for that is, ATP. The set of chemical reactions involved in this process is termed as cellular respiration. It may include glycolysis, Krebs cycle, electron transport chain, oxidative phosphorylation.

ATP hydrolysis:

Organisms use the energy associated with ATP through a hydrolysis reaction. The hydrolysis of ATP releases ADP, Pi,  and energy. ADP is further hydrolyzed to produce AMP, Pi, and energy.

Piper accidentally cuts her finger while chopping vegetables. Why does she feel pain?
The nerves can’t transmit an action potential.
Nerves in the finger detect stimuli and send the message to the brain.
The nerves signal the arteries to stop circulation to the area.
Nerves send a reflexive action through the spinal cord.

Answers

Nerves in the finger detect stimuli

Answer:

Nerves in the finger detect stimuli and send the message to the brain

Explanation:

When Piper cuts her finger, the pain receptors on her finger skin sense the cut and transmit the message to the brain. This is done via nerve cells which communicate with each other and transmit the message. The dendrites of a nerve cell pick up the pain signal and it is passed through the axon and the synaptic cleft to the next nerve cell. Likewise, the process continues and finally the central nervous system receives the message and she feels the pain.

Click on the true statements about dna. (select all that apply.)

Answers

Options are not provided so I have mentioned all possible answers for this question.
Following statements are true about DNA:
1. DNA stands for Deoxyribose Nucleic Acid.
2. It is a double helical structure.
3. Both the strands run opposite in direction.
3. All our DNA are located in nucleus and some are also present in the mitochondria.
4. DNA is composed of acids, phosphates, sugars and bases.
5. The four bases that make up DNA are A, G, T and C.
6. The sugar present in DNA is deoxiribose sugar.
7. It carries the genetic information of an organism.

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